Background: Family caregivers to persons living with dementia are at risk of financial strain from the high out-of-pocket costs of care and reduced employment opportunities. Financial strain disproportionately affects U.S.
View Article and Find Full Text PDFNuclear speckles are membraneless organelles that associate with active transcription sites and participate in post-transcriptional mRNA processing. During the cell cycle, nuclear speckles dissolve following phosphorylation of their protein components. Here, we identify the PP1 family as the phosphatases that counteract kinase-mediated dissolution.
View Article and Find Full Text PDFBackground Despite multiple policy statements from the American Academy of Pediatrics (AAP) and other societies, trampoline is a popular recreational activity among children, leading to multiple injuries. This study aimed to present the hospitalization rate due to trampoline-related injuries in the United States and describe the range of pediatric injuries. Materials and methods A cross-sectional analysis was performed utilizing the Kids' Inpatient Database for 2019.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
December 2024
The very first representative of trithia-bridged N-heterotriangulene, a triphenylamine with sulfur atoms bridging the ortho-positions, was synthesized by a sequence of regioselective sulfenylation with phthalimidesulfenyl chloride followed by Lewis acid-catalyzed electrophilic cyclization. X-ray crystallography revealed a saddle-shaped geometry of the polycyclic scaffold. UV/Vis absorption spectroscopy and cyclic voltammetry were used to characterize the optoelectronic properties.
View Article and Find Full Text PDFThis pilot study evaluated a money management skills program for students within the scope of occupational therapy practice. Three undergraduate students with intellectual disabilities attended sessions twice weekly for six weeks, learning financial concepts and applying knowledge through technology-based activities. The students were nonrandomly selected through a program that works to support college students with intellectual disabilities.
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