Publications by authors named "K H Knuth"

Article Synopsis
  • This exploratory study examines the differences in self-reported COVID-19 vaccine side effects and breakthrough infections between individuals with diabetes and those without diabetes.
  • The research was conducted using data from adult participants in the U.S. who voluntarily provided information about their health, vaccinations, and any side effects experienced.
  • Results indicated that individuals with diabetes reported fewer side effects after vaccination compared to those without diabetes, highlighting potential differences in vaccine reactions based on diabetic status.
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In January 2021, 999 COVID-19 positive adults in the US enrolled in an online, direct-to-patient registry to describe daily symptom severity and progression over 28 days. The most commonly reported and persistent symptoms were fatigue, headache, decreased sense of taste, decreased sense of smell, and cough. Fast resolving symptoms included gastrointestinal symptoms (nausea, vomiting, diarrhea) and those related to fever and chills.

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Objective: To describe cognitive symptoms in people not hospitalised at study enrolment for SARS-CoV-2 infection and associated demographics, medical history, other neuropsychiatric symptoms and SARS-CoV-2 vaccination.

Design: Longitudinal observational study.

Setting: Direct-to-participant registry with community-based recruitment via email and social media including Google, Facebook and Reddit, targeting adult US residents.

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Article Synopsis
  • COVID-19 has underscored the necessity for improved pharmacovigilance methods, leading to a study using community volunteers to track vaccine effectiveness and the characteristics of breakthrough infections.
  • Between December 2020 and September 2021, over 11,800 volunteers provided data on their vaccination status and COVID-19 symptoms, revealing that fully vaccinated individuals had a lower incidence of infection compared to partially vaccinated and unvaccinated groups.
  • The findings indicated that most breakthrough infections in fully vaccinated individuals were asymptomatic or mild, and the study supports the value of patient-reported data in assessing vaccine impact and infection severity.
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Objective: The objective of this study was to describe the acute side effects experienced by pregnant women who received a coronavirus disease 2019 (COVID-19) vaccine in the United States and to compare their experience to nonpregnant women of similar age.

Study Design: Adults who received a COVID-19 vaccine in the United States were invited via social media to enroll in an online, longitudinal, community-based registry ( www.helpstopCOVID19.

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