Publications by authors named "K H Bachmann"
Introduction: Use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is still in the focus of research, in which pigs are commonly involved. During VA-ECMO, cardiovascular parameters are artificially manipulated and therefore not reliable indicators of nociception. Nociceptive withdrawal reflex (NWR) thresholds can be a suitable alternative in such a context.
View Article and Find Full Text PDFPurpose: Gastrointestinal (GI) dysfunction is common in critically ill patients and associated with poor outcomes. There is a lack of standardised methods for daily monitoring of GI function. COSMOGI aimed to develop a Core Outcome Set (COS) for daily monitoring of GI function to improve consistency and comparability in future studies in critically ill patients.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to establish clear cutoff points for low, intermediate, and high doses of norepinephrine (noradrenaline), a key vasopressor in intensive care, to better assess patient mortality linked to cardiovascular support.
- Researchers analyzed data from over 8,000 ICU patients in Finland and validated the findings with a larger dataset from the U.S., focusing on the highest norepinephrine doses administered within the first 24 hours.
- The identified dose ranges were low (<0.2 μg/kg/min), intermediate (0.2-0.4 μg/kg/min), and high (>0.4 μg/kg/min), with increasing mortality rates correlating with higher doses, demonstrating a significant relationship between norepine