Publications by authors named "K Gumustekin"
Background/aim: There is no information on the dose-response relationship of curcumin on the hemodynamic variables of the heart at the organ level in isolated perfused rat hearts. We aimed to investigate the effects and mechanisms of curcumin on the hemodynamic variables of isolated perfused rat hearts.
Materials And Methods: Rats were randomly divided into 9 groups.
Plasma homocysteine and liver tissue S-adenosylmethionine, S-adenosylhomocysteine status in vitamin B6-deficient rats.
Eur Rev Med Pharmacol Sci
January 2015
Objective: The aim of this study was to evaluate plasma homocysteine (Hcy), malondialdehyde (MDA), glutathione (GSH) levels, glutathione peroxidase (GSH-Px) and glutathione-S-transferase (GST) activities and liver tissue S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) levels in control and vitamin B6-deficient rats.
Materials And Methods: Thirty-two male rats with a weight of 65-75 g were used for the experiment. The rats were divided into control (n=16) and vitamin B6-deficient groups.
The present study examined the heart rate turbulence (HRT) and heart rate variability (HRV) parameters in healthy young smokers (<40 years) to assess the effects of smoking on cardiac autonomic function. The study included 75 smokers with a history of habitual smoking for at least 1 year (41 males and 34 females; mean age, 29.3 ± 7.
View Article and Find Full Text PDFBackground: Intra-abdominal hypertension (IAH) has negative effects on the functions of intra- and extra-abdominal organs and systems. Intra- and extraperitoneal hemorrhage, diffuse intestinal and retroperitoneal edema, intestinal ileus or obstruction, necrotizing pancreatitis, intra-abdominal packing, intra-abdominal sepsis, and pneumoperitoneum can all cause IAH. No studies were found in the literature relating to the effects of IAH on the endocrine functions of the pancreas.
View Article and Find Full Text PDFArticle Synopsis
- The study examined how vitamin E and Hippophae rhamnoides extract affect oxidative stress in rat livers caused by nicotine exposure.
- The rats were divided into four groups and were treated for three weeks, with some receiving nicotine alone and others supplemented with either vitamin E or HRe-1.
- Results showed that both vitamin E and HRe-1 reduced nicotine-induced increases in oxidative stress indicators, indicating they might help protect the liver from nicotine-related damage.