Int Arch Occup Environ Health
January 2020
Purpose: Due to a potential exposure to several definite or probable carcinogens, the IARC classified manufacturing of art glass, glass containers, and pressed ware as probably carcinogenic to humans in 1993 (Group 2A). Purpose of this study was to update the evidence from recently published scientific reports.
Methods: We searched for peer-reviewed articles published between 1993 and 2018 and combined result in terms of a meta-analysis.
Objectives: To estimate a threshold value for the respirable quartz dust concentration and silicosis incidence (1/1, ILO 1980/2000) in the German porcelain worker cohort.
Methods: Forty incident cases occurred among 17,144 workers. Estimation of the relationship to cumulative respirable quartz dust exposures by using Cox regression with restricted cubic splines (7 knots or less) and fractional polynomials (degrees 5 or less).