Myocardial infarction and transient ventricular dysfunction in an adolescent with sickle cell disease.

We report a case of an adolescent who had sickle cell disease and previous evidence of myocardial damage and presented with abdominal pain and rapid progression to cardiogenic shock and subsequent development of myocardial infarction. To our knowledge, this represents only the second report of a case of acute myocardial ischemia and subsequent infarction resulting transient ventricular dysfunction reported in a child with sickle cell disease successfully treated with exchange transfusion. The pathophysiology of this complication remains unclear, and cardiac complications may remain undetected as lung, bone, and brain infarcts are more common and the pain associated with sickle cell crisis may mask the ischemic symptoms.

Evaluation of remote stethoscopy for pediatric telecardiology.

Objective: To investigate the interobserver reliability and diagnostic validity of a commercial electronic stethoscope for pediatric telecardiology.

Materials And Methods: Pairs of blinded pediatric cardiologists made independent diagnoses, recommendations concerning follow-up echocardiography, and specific judgments regarding heart sounds, murmurs, and congenital heart disease using an electronic (ES) or an acoustic (AS) stethoscope on 78 pediatric cardiology outpatients and at a distance of 450 km (280 miles) with 38 telemedicine cardiology outpatients. The kappa statistic (K) indexed the instruments' interexaminer reliabilities.

[The influence of modified sequential therapy on lipid metabolism in postmenopausal women].

The study was performed in 50 women aged 49 to 55 years, divided into two groups. Group I received transdermally at a rising dose of 2 to 8 mg, altogether 16 mg during the therapeutic cycle of 20 days. Group II received estriol intravaginally 0.

Balloon pulmonary valvuloplasty for isolated pulmonary valvular stenosis.

Fifteen balloon pulmonary valvuloplasties (BPVs) were performed on 13 infants and children with isolated pulmonary valvular stenosis (PVS). There were no complications. Two patients required repeat BPV, one for failure, the other for restenosis.