Senolytic agent ABT-263 mitigates low- and high-LET radiation-induced gastrointestinal cancer development in mice.

Exposure to ionizing radiation (IR), both low-LET (e.g., X-rays, γ rays) and high-LET (e.

Effectiveness of Braille and ATP Technique in Improving Oral Hygiene Status of Visually Impaired Children: An Interventional Study.

Aim: The study aimed to subject two groups of visually challenged children to Braille and audio-tactile performance (ATP) techniques of oral health education and compare the effectiveness of each technique through a comparison of OHI-S index scores.

Materials And Methods: 30 visually challenged children of 6-12 years belonging to a Government-aided blind school were divided into two study groups based on the method of oral health education ( = 15). Group I received oral hygiene instructions in Braille while group II received instructions through audio clips, tactile sensations of tooth models, and closely supervised performance of brushing technique.

Caregiver‐Driven Cognitive training (CDCT) – A feasible approach to dementia care in the Indian Population.

Background: Dementia care is incomplete without active caregiver involvement. Yet, existing cognitive interventions often overlook this crucial aspect. This study aims to develop and evaluate the feasibility of a Caregiver Driven Cognitive Training (CDCT) program in the Indian context, recognizing caregivers as essential partners in the care process.

Toward Resilient Maternal, Neonatal and Child Health Care: A Qualitative Study Involving Afghan Refugee Women in Pakistan.

Background: Afghan refugees in Pakistan, particularly in Quetta, Balochistan, encounter formidable barriers in accessing maternal, newborn, and child health (MNCH) services. These challenges have been intensified by the COVID-19 pandemic and entrenched systemic health inequities.

Methods: This qualitative study, conducted from February to April 2023, aimed to assess the obstacles within health systems and community environments that hinder MNCH service access among Afghan refugees.

Unveiling the potential of Hamigeran-B from marine sponges as a probable inhibitor of Nipah virus RDRP through molecular modelling and dynamics simulation studies.

The Nipah virus (NiV) is an emerging pathogenic paramyxovirus that causes severe viral infection with a high mortality rate. This study aimed to model the effectual binding of marine sponge-derived natural compounds (MSdNCs) towards RNA-directed RNA polymerase (RdRp) of NiV. Based on the functional relevance, RdRp of NiV was selected as the prospective molecular target and 3D-structure, not available in its native form, was modelled.