Publications by authors named "K Ghani"
Understanding renal pelvis pressure (P) during ureteroscopy (URS) has become increasingly important. High irrigation rates, desirable to maintain visualization and limit thermal dose, can increase P. Use of a multi-channel ureteroscope (m-ureteroscope) with a dedicated drainage channel is one strategy that may facilitate simultaneous low P and high flowrate.
View Article and Find Full Text PDFStent Omission after Ureteroscopy and Lithotripsy (SOUL) in the Michigan Urological Surgery Improvement Collaborative (MUSIC): study protocol for a pragmatic prospective combined randomized and observational clinical trial.
Russell E N Becker Stephanie Daignault-Newton Elaina Shoemaker Dennis Sitek Jennifer M Thelus Khurshid R Ghani
Trials
December 2024
Article Synopsis
- - Ureteral stents are commonly used after ureteroscopy to prevent complications from kidney stones, yet they can cause significant pain and urinary issues, which has led to calls for their omission in many cases.
- - Guidelines support not using stents in uncomplicated surgeries, but over 80% of procedures still involve them, partly due to insufficient evidence about their impact on pain and patient outcomes.
- - A new study is being conducted where patients randomly choose whether to have a stent or not, while those who refuse randomization will be observed based on the doctor's decision, aiming to gather real-world data on the effectiveness of stent omission.
Article Synopsis
- - Over the last 30 years, miniaturized percutaneous nephrolithotomy (mPCNL) has gained popularity due to its potential to reduce complications compared to standard procedures, but there's still debate over best practices and management strategies that hinders wider use.
- - An international panel of urology experts developed a consensus document on mPCNL to provide a comprehensive framework for practice, which included reviewing literature, identifying research gaps, and conducting surveys to gather expert opinions.
- - The study revealed 58 key questions on mPCNL practices, and consensus was achieved on 30 questions, affirming mPCNL as an effective technique for treating upper urinary tract stones in both adults and children.
Article Synopsis
- - Clinical trials for cancer often face low enrollment due to unnecessary kidney function eligibility criteria, which limit the number of eligible patients and complicate the screening process while creating inequity in access to trials.
- - An analysis of phase 3 urologic oncology trials from 2007 to 2021 revealed that 35% of trials listed kidney function restrictions, but 41% of those trials tested interventions that had no possible impact on renal function.
- - The findings indicate a disconnect between trial exclusions based on kidney function and the actual effects of interventions, suggesting that revising eligibility criteria could improve trial access and effectiveness.