Image-Based Measures of Obesity are Associated with Alterations in Metabolic Pathways in Non-small Cell Lung Cancer.

Background: Studies suggest that the obesity paradox in non-small cell lung cancer (NSCLC) results from the use of body mass index (BMI) as a measure of obesity. However, the mechanistic basis linking body fat and lung cancer behavior remains unclear. We examined the association of image-based measures of obesity with tumor gene expression to identify transcriptional signatures concordant with adiposity and their underlying biology.

Starship super heavy acoustics: Far-field noise measurements during launch and the first-ever booster catch.

Far-field (9.7-35.5 km) noise measurements were made during the fifth flight test of SpaceX's Starship Super Heavy, which included the first-ever booster catch.

The Impact of Infections in Patients Treated with Atezolizumab Plus Bevacizumab for Unresectable Hepatocellular Carcinoma.

: The therapeutic landscape of unresectable hepatocellular carcinoma (uHCC) continues to evolve. Atezolizumab, an anti-programmed cell death ligand 1 (PD-1) immune checkpoint inhibitor (ICI), in combination with bevacizumab, has substantially improved outcomes. This study aims to evaluate the incidence, risk factors, and outcomes in patients who develop infections while receiving atezolizumab and bevacizumab for uHCC.

Toward a dynamic national transportation noise map: Modeling temporal variability of spectral traffic noise emission levels.

The National Transportation Noise Map predicts time-averaged road traffic noise across the continental United States (CONUS) based on annual average daily traffic counts. However, traffic noise can vary greatly with time. This paper outlines a method for predicting nationwide hourly varying source traffic sound emissions called the Vehicular Reduced-Order Observation-based Model (VROOM).