Publications by authors named "K Galesic"
J Am Soc Nephrol
October 2024
Article Synopsis
- A retrospective study of 183 adult patients treated with rituximab for podocytopathies showed that 82% achieved complete or partial remission within 6 months.
- *Long-term follow-up revealed that 55% of initial responders maintained relapse-free survival over three years, with improved outcomes linked to maintenance therapy.
- *Patients on maintenance therapy experienced significantly fewer relapses per year and maintained stable kidney function compared to non-responders.
J Clin Med
September 2024
Article Synopsis
- The study investigates the role of C4d deposits in patients with primary IgA nephropathy (pIgAN) and finds that C4d is present in 45.3% of patients, indicating activation of the lectin pathway of the complement system.*
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- C4d-positive patients exhibited worse renal health outcomes, such as higher blood pressure, increased proteinuria, and lower eGFR, leading to faster progression to kidney failure.*
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- The findings suggest that C4d can serve as an independent predictor of disease progression in pIgAN, but the implications for treatment using complement inhibitors remain unclear.*
