[Psychosomatic correlations in patients with hypertension and renal arterial hypertension].

Psychosomatic status was investigated in 104 patients with essential hypertension (EH) and 111 patients with secondary arterial hypertension (AH) of renal origin in the presence of chronic pyelonephritis. A significant heterogeneity of psychological characteristics was established in patients with these two clinical forms of AH. In EH patients psychological deviations were detected since very early stages of the disease, but they did not become more profound with stabilisation of blood pressure.

[Diastolic relaxation and left ventricular blood filling in patients with hypertension].

Disorders of left-ventricular diastolic relaxation and blood filling in patients with first- and second-stage essential hypertension are shown, by means of echo-, radio- and apexcardiography, to be due to the effects of arterial blood pressure, hemodynamic changes, heart rate and the magnitude of left-ventricular hypertrophy. Antihypertensive treatment, affecting major parameters of disease, brings about the recovery of the heart's diastolic function.

[Possible reverse development of myocardial hypertrophy and ischemia in patients with hypertension after short-term antihypertensive therapy].

The effects of short-term antihypertensive therapy were assessed using echo- and electrocardiography, in patients with first- or second-stage essential hypertension, with respect to possible reverse development of left-ventricular hypertrophy and myocardial ischemia. A reduction of left-ventricular hypertrophy was found to be possible, with regard to the hemodynamic type, in patients with mild or moderate essential hypertension provided their blood pressure was controlled effectively. Reverse development of electrocardiographic signs of myocardial ischemia (ST segment and T wave reaching their normal values) is possible through a decrease of arterial BP and a reduction of adrenergic effects on the heart.

[Treatment of arterial hypertension with calcium antagonists].

The antihypertensive effect of finoptin (verapamil) and corinfar (nifedipin) and their impact on the hemodynamics and the repolarization complex of the ECG were studied in 52 patients with essential hypertension and 48 patients with secondary arterial hypertension. The calcium antagonists were found to effectively decrease the blood pressure by reducing the peripheral resistance. Verapamil may be recommended for the monotherapy of mild and moderate forms of arterial hypertension, whereas corinfar should be used in cases of marked hypertension and at the third stage of therapy.