Comparative analysis of WC1.1+ and WC1.2+ γδ T cell subset responses from cattle naturally infected with Mycobacterium bovis to repeat stimulation with mycobacterial antigens.

Mycobacterium bovis (M. bovis) causes bovine tuberculosis (bTB). The challenges in controlling and eradicating this zoonotic disease are compounded by our incomplete understanding of the host immune response.

Feasibility Testing of a Nurse-Invented Urinary Drainage Bag Securement Device.

Purpose/aims: To determine the feasibility of a nurse invention called the Bag Below Bladder (B3) Buddy using validated usability and acceptability tools, in securing urinary drainage bags while patients ambulate.

Design: An intervention study was implemented in a participant dyad consisting of a patient and clinician. Each dyad used the B3 Buddy in 1 encounter, ambulating at least 90 ft in an inpatient unit.

vaccination and subsequent experimental infection outcomes are associated with changes in vitamin D status in dairy calves.

Investigations into the role of vitamin D (vitD) in the immune response of cattle are limited. The objectives of this study were therefore to investigate the association between circulating vitD concentration, tuberculosis (TB) vaccination, and infection outcomes in 24 dairy calves (<8 wk old) that were housed throughout and fed a BW-based allowance. The study design incorporated 2 phases: vaccination (experimental wk 0-52) and experimental infection phase (wk 52-65).

Hyper-induction of IL-6 after TLR1/2 stimulation in calves with bovine respiratory disease.

Bovine respiratory disease (BRD) is a leading cause of mortality and compromised welfare in bovines. It is a polymicrobial syndrome resulting from a complex interplay of viral and bacterial pathogens with environmental factors. Despite the availability of vaccines, incidence and severity in young calves remains unabated.