Publications by authors named "K G Magdesian"
Knowledge of immunodeficiencies is crucial to neonatal medicine, in that they predispose to sepsis in the newborn and neonatal foal, as well as recurrent infections in older foals. The most common immunodeficiency in newborn and neonatal foals is failure of passive transfer, which is an example of an acquired immunodeficiency. Congenital or developmental immunodeficiencies may be transient or permanent, and can either affect the cell-mediated or humoral arms of immunity, and in some cases both.
View Article and Find Full Text PDFA newborn (5 h old) quarter horse colt was presented because of lethargy and severe abdominal distention. Uroperitoneum was suspected during initial workup, based on sonographic imaging and peritoneal fluid analysis. Definitive diagnosis was confirmed during exploratory celiotomy.
View Article and Find Full Text PDFAlloimmune disorders occur in foals when pregnant mares produce antibodies against antigens on the foal's cells or tissues, and concentrate them within colostrum. Once foals nurse and absorb colostral antibodies, they can develop hematologic or cutaneous manifestations that can occur individually or in combination. These include neonatal isoerythrolysis, a hemolytic anemia directed against factors on the foal's erythrocytes, alloimmune thrombocytopenia when the antibodies are directed against platelet antigens, alloimmune neutropenia when they are directed against neutrophil antigens, and a combination of suspected alloimmune ulcerative dermatitis, neutropenia and thrombocytopenia.
View Article and Find Full Text PDFArticle Synopsis
- Hematology serves as a diagnostic tool for assessing the health of horses, with a focus on comparing blood count variables among Warmbloods, Thoroughbreds, and stock horses.
- The study involved 96 healthy horses, with blood samples analyzed using statistical methods to determine differences in blood cell counts and protein levels by breed.
- Results showed Warmbloods had lower total white blood cell and lymphocyte counts, while Thoroughbreds had higher red blood cell counts and lower total protein levels compared to stock horses, indicating the need for breed-specific interpretations in veterinary hematology.
Background: Fecal microbiota transplant (FMT) is increasingly administered as part of the treatment of colitis in horses, yet there is little data as to its effectiveness.
Aim: Retrospective evaluation of the effects of FMT on discharge status, fecal consistency, length of hospitalization, and improvement in clinical signs in horses hospitalized for diarrhea.
Methods: Retrospective case-control study.