Publications by authors named "K G Kostopoulos"
The implementation of speckle tracking echocardiography for cardiac resynchronization therapy optimisation. A rotational myocardial mechanics interpretation.
Alexandros Stefanidis Paraskevi Korlou Panagiotis Margos Ignatios Ikonomidis Ioannis Paraskevaidis Konstantinos Kostopoulos
Echo Res Pract
December 2024
Article Synopsis
- Cardiac resynchronization therapy (CRT) enhances left ventricular function in heart failure patients, but its mechanisms remain partly unclear; this study aimed to investigate these mechanisms using 2D speckle tracking echocardiography (2D-STE).
- The study involved 46 patients who underwent CRT and evaluated their cardiac performance at baseline and post-CRT implementation through 2D-STE and a 6-minute walk test, observing a 48% response rate at 6 months, particularly in those with dilated cardiomyopathy.
- Optimizing CRT by adjusting the activation timing of the ventricular electrodes was found to significantly improve left ventricular function, with improvements in effective stroke volume and rotational mechanics serving as key indicators of successful therapy
Article Synopsis
- Research on how organizations react to performance across multiple goals is limited, often focusing only on search intensity without considering where that search happens.
- This study uses behavioral theory to show that when performance on a main goal is below expectations, organizations increase their search efforts both within familiar technologies and in the external environment.
- However, if performance on a secondary goal is high despite poor primary goal performance, organizations tend to reduce their search efforts, suggesting that feedback on multiple, unevenly important goals influences strategic decision-making.
Newly detected diabetes mellitus patients with acute coronary syndrome have an adverse cardiometabolic profile similar to patients with prior diabetes and a more extensive ischemic myocardial insult.
Loukianos S Rallidis Konstantinos A Papathanasiou Donatos Tsamoulis Vasileios Bouratzis Ioannis Leventis Konstantinos Kostopoulos
Diabetes Res Clin Pract
May 2024
Aims: The impact of newly detected diabetes mellitus (NDDM) on metabolic parameters and extent of myocardial necrosis in patients with acute coronary syndrome (ACS) is not fully explored. We examined the impact of NDDM on cardiometabolic characteristics and myocardial necrosis in ACS patients.
Methods: CALLINICUS-Hellas Registry is an ongoing prospective multicenter observational study evaluating the adherence to lipid-lowering therapy (LLT) among ACS patients in Greece.