[A simple method of testing the sensitivity to antineoplastic agents on human tumors in vivo].

BRO human melanoma cells, encapsulated in fibrinogen clots and implanted under the subrenal capsule of immunosuppressed mice, serve as a model for evaluating the effects of chemotherapeutic agents on human tumors in vivo. Histological examination of 8-day tumors in mice which had received 4.5 Gy prior to implantation, showed that the cells were largely viable.