Publications by authors named "K G Byrnes"

Article Synopsis
  • Metabolic-dysfunction associated steatohepatitis (MASH) is linked to conditions like obesity and diabetes, leading to liver problems and cardiovascular disease, but identifying it in patients can be difficult.* -
  • Researchers developed targeted peptide radiotracers for PET imaging to visualize changes in macrophage populations in the liver of mice with MASH, observing a decrease in resident macrophages and an increase in recruited ones during disease progression.* -
  • The study found a strong correlation between the PET imaging results and tissue analysis, suggesting that these radiotracers could be useful for non-invasive diagnostics and monitoring of MASH in humans.*
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Article Synopsis
  • Pancreatic heterotopia (PH) is when pancreatic tissue forms in the gastrointestinal tract and can have various health issues, though cancer development in PH is very uncommon.
  • A study reviewed 163 PH cases from 1990 to 2020, finding that 7 had neoplastic processes, including different types of tumors.
  • Most affected patients were men around 64 years old, with symptoms such as weight loss and abdominal pain, and it’s critical for pathologists to identify PH to ensure correct diagnosis and staging of potential tumors.
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Background: Since the ileal pouch anal anastomosis (IPAA) was first described, anorectal manometry (ARM) has been used to study its physiology and function. Few studies have investigated if preoperative ARM can predict pouch function.

Methods: Pubmed, EMBASE, and the Cochrane Library databases were systematically searched.

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Objective: The objective of this study was to report the 12-month oncological outcomes for patients with non-muscle-invasive bladder cancer (NMIBC) within the prospective, international COVIDSurg Cancer study.

Patients And Methods: Eligible patients were aged ≥18 years and scheduled for elective surgical management of NMIBC with curative intent (transurethral resection of bladder tumour [TURBT] or bladder biopsy) from 21 January to 14 April 2020. The primary outcome was disease recurrence within 12 months of previous elective TURBT/bladder biopsy.

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