[Influence of phenamin on the reaction of cortical neurons evoked by stimulation of mesodiencephalic structures].

Experiments set upon 32 cats demonstrated that d, l-amphetamine (1-3 mg/kg, intravenously) augmented the number of responding units, modified the structure of the response and the intensity of the reaction from the sensorimotor (somatosensory) cortex neurones following stimulation of the mesencephalic reticular formation. Weakening of phasical and significant intensification of tonic reactions from the lateral hypothalamus was noted, this being attended by a rise of areactive neurones. A single stimulation of the antero-medial hypothalamus evoked inhibitory responses more often than it did in controls.

Comparative effect of amphetamine and caffeine on spontaneous activity of sensomotor cortical units and their responses to stimulation of the caudate nucleus.

In acute experiments on anesthetized cats activity of sensomotor cortical units was recorded during low-frequency stimulation of the head of the caudate nucleus. Amphetamine (1 mg/kg), although not significantly affecting the spontaneous firing rate, increased the number of spontaneously active cortical units. Meanwhile inhibition of these units during stimulation of the caudate nucleus was weakened.