Publications by authors named "K Funaki"

Article Synopsis
  • The Briganti nomogram, with a 5% cut-off, is used to decide if pelvic lymph node dissection (PLND) is necessary for prostate cancer patients.
  • A study analyzed data from 1,068 patients who had radical prostatectomy and found no significant oncological benefit of PLND for those with a Briganti score of 5%.
  • High PSA levels and advanced T-stage were linked to worse biochemical recurrence-free survival, while PLND did not have a meaningful impact on recurrence outcomes.
View Article and Find Full Text PDF

Objectives: Currently available questionnaires have limited ability to measure physical activity (PA) using accelerometers as a gold standard. This study aimed to develop a PA questionnaire for middle-aged Japanese workers and propose a PA scoring system for predicting low moderate-to-vigorous PA (MVPA).

Methods: A total of 428 participants (median age 49 years; 75.

View Article and Find Full Text PDF

Background: Segmental absence of intestinal musculature (SAIM) is a partial defect of the intrinsic muscular layer of the intestinal tract. In this report, we describe a case of perforation of the sigmoid colon due to SAIM accompanied by vascular Ehlers-Danlos syndrome (vEDS), which was successfully treated by surgical therapy.

Case Presentation: A male in his 30 s was being followed up for vEDS diagnosed by genetic testing.

View Article and Find Full Text PDF

We report the synthesis of a peptide nucleic acid (PNA) monomer containing N-bis(aminomethyl)benzoylated cytosine (C base). The C monomer was incorporated into PNA oligomers using Fmoc-based solid-phase synthesis. The C base in PNA had two positive charges and exhibited greater affinity for DNA G base than the natural C base.

View Article and Find Full Text PDF

Purpose: Cerebrospinal fluid drainage (CSFD) is recommended during open or endovascular thoracic aortic repair. However, the incidence of CSFD complications is still high. Recently, CSF pressure has been kept high to avoid complications, but the efficacy of CSFD at higher pressures has not been confirmed.

View Article and Find Full Text PDF