Publications by authors named "K Fukuma"
Background: Adrenomedullin has angiogenic and vasoprotective effects in acute ischemic stroke (AIS). This investigator-initiated trial aimed to evaluate the safety, efficacy, and optimal administration of adrenomedullin in treating AIS.
Methods: In this single-center, multi-cohort, double-blinded, randomized, placebo-controlled, Phase II trial, patients with AIS received pulsed adrenomedullin (9 ng/kg/min for 8 h daily over 7 days) or placebo in the first-half cohort, and continuous-pulsed adrenomedullin (9 ng/kg/min for 72 h during the first 3 days and 8 h daily between Day 4-7) or placebo in the second-half cohort.
Poststroke epilepsy (PSE) is associated with higher mortality and poor functional and cognitive outcomes in patients with stroke. With the remarkable development of acute stroke treatment, there is a growing number of survivors with PSE. Although approximately 10% of patients with stroke develop PSE, given the significant burden of stroke worldwide, PSE is a significant problem in stroke survivors.
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- * The study involved 142 subjects split into older (≥65 years) and younger (≤39 years) groups, measuring the muscle area using ultrasound.
- * Found that cut-off values for identifying low geniohyoid muscle mass were 172.5 mm for women and 194.7 mm for men, useful for diagnosing sarcopenic dysphagia.
Article Synopsis
- The study explores the potential link between high-pillow usage and spontaneous vertebral artery dissection (sVAD), aiming to assess whether using taller pillows increases the risk of developing this condition.
- Researchers compared 53 patients with sVAD to 53 age- and sex-matched controls, finding that high-pillow usage was significantly more common in patients with sVAD (34% vs 15% for pillows 12–15 cm high).
- The findings suggest that about 10% of sVAD cases may be linked to high-pillow use, indicating that it could represent a specific condition referred to as "Shogun pillow syndrome."
Objective: Postseizure functional decline is a concern in poststroke epilepsy (PSE). However, data on electroencephalogram (EEG) markers associated with functional decline are scarce. Thus, we investigated whether periodic discharges (PDs) and their specific characteristics are associated with functional decline in patients with PSE.
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