Publications by authors named "K Fujiyoshi"
Background: Higher levels of high-sensitivity C-reactive protein (hsCRP) are associated with increased risk of cardiovascular events in patients with coronary artery disease (CAD).
Aims: To elucidate the characteristics of coronary plaques in patients with CAD with high hsCRP levels.
Methods: A total of 793 consecutive patients with stable CAD who underwent optical coherence tomography (OCT) of the culprit vessel during percutaneous coronary intervention were included.
Article Synopsis
- The study investigates the distribution of lymph nodes around the inferior mesenteric artery (IMA) in patients with advanced left-sided colorectal cancer, as complete lymph node dissection is recommended but can lead to complications.
- It involved 30 patients who underwent surgery, where lymph nodes and associated vessels were closely examined, finding that the main lymph nodes were present in 26 patients with varying numbers of nodes dissected.
- The results indicate that most of the main lymph nodes are located near the left colic artery bifurcation, making this area crucial for effective lymph node dissection in advanced cases.
Phosphorylated tyrosine is a fundamental building block of bioactive peptides and proteins. However, the chemoselective phosphorylation of tyrosine over other nucleophilic amino acid residues in unprotected peptides remains a significant challenge. Here we report an umpolung strategy that converts the C-terminal tyrosine into an electrophilic spirolactone cyclohexadienone motif through hypervalent iodine oxidation, followed by a 1,2-phospha-Brook rearrangement using phosphite diesters as nucleophilic phosphoryl donors.
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- This study compared postoperative outcomes for 49 patients with lower rectal cancer who underwent low anterior resection (LAR) or intersphincteric resection (ISR) regarding anal function and quality of life (QOL).
- Key findings showed that while some anorectal manometry results were similar, patients in the ISR group had worse maximum resting pressure and higher fecal incontinence scores compared to the LAR group.
- The research suggests that surgical technique plays a significant role in affecting anal function and fecal incontinence outcomes, but cautions against over-relying on combined assessment methods when evaluating these relationships.
Article Synopsis
- - The study aimed to evaluate the effectiveness of the long cortical bone trajectory (CBT) technique in achieving lumbar spinal fusion and to identify factors that affect the time taken for fusion among patients undergoing this surgery for degenerative spondylolisthesis.
- - A total of 167 patients were analyzed, with results showing a high bone fusion rate of 95.8% by the last follow-up, averaging a fusion time of about 16.6 months post-surgery, but found no significant impact from specific surgical techniques on fusion times.
- - Key independent factors affecting the time to fusion included patient age, sex (females took longer), and BMI, highlighting the importance of these demographic variables over technical procedural choices.