Validation of a clinician-administered diagnostic measure of ICD-11 PTSD and complex PTSD: the International Trauma Interview in a clinical sample of military veterans.

The International Trauma Interview (ITI) is the first clinician-administered diagnostic tool developed to assess posttraumatic stress disorder (PTSD) and Complex PTSD (CPTSD), both recently recognized in the ICD-11. The current study aims to test the construct and discriminant validity of the ITI in a population of treatment-seeking veterans. 124 Danish veterans seeking psychological treatment were interviewed by a group of trained clinicians for ICD-11 PTSD and CPTSD before beginning treatment at the Military Psychological Department in the Danish Defense.

Loneliness is associated with adverse health behaviour and obesity: a Danish population-based study of 122,258 individuals.

Background: Loneliness is a public health concern associated with increased morbidity and mortality. Adverse health behaviours and a higher body mass index (BMI) have been proposed as key mechanisms influencing this association. The present study aims to examine the relationship between loneliness, adverse health behaviour and a higher BMI, including daily smoking, high alcohol consumption, physical inactivity, unhealthy dietary habits, and obesity in men and women and across different life stages.

Economic, cultural, and social inequalities in potentially inappropriate medication: A nationwide survey- and register-based study in Denmark.

Background: Potentially inappropriate medication (PIM) is associated with negative health outcomes and can serve as an indicator of treatment quality. Previous studies have identified social inequality in treatment but often relied on narrow understandings of social position or failed to account for mediation by differential disease risk among social groups. Understanding how social position influences PIM exposure is crucial for improving the targeting of treatment quality and addressing health disparities.

NHCl-induced metabolic acidosis increases the abundance of HCO transporters in the choroid plexus of mice.

Regulation of cerebrospinal fluid (CSF) pH and brain pH are vital for all brain cells. The acute regulation of CSF pH is dependent on the transport of HCO across the choroid plexus in the brain ventricles. Acute regulation in response to acidosis is dependent on H export and HCO import across the plasma membrane.

Mechanisms of cerebrospinal fluid secretion by the choroid plexus epithelium: Application to various intracranial pathologies.

The choroid plexus (CP) is a small yet highly active epithelial tissue located in the ventricles of the brain. It secretes most of the CSF that envelops the brain and spinal cord. The epithelial cells of the CP have a high fluid secretion rate and differ from many other secretory epithelia in the organization of several key ion transporters.