Publications by authors named "K Fiebig"
Article Synopsis
- The study investigated the relationship between testosterone levels, muscle mass, and strength in pre-menopausal females undergoing a 12-week resistance training program, finding no link with total circulating testosterone.
- Bioavailable testosterone and the localization of androgen receptors (AR) in the nucleus were positively associated with muscle mass and strength, suggesting a unique role of these factors in muscle development for females.
- In vitro experiments indicated that high doses of testosterone increased muscle cell size without activating the previously assumed Akt/mTOR pathway, instead enhancing the nuclear presence of the AR.
Background: Androgenetic alopecia (AGA) affects almost half the population, and several treatments intending to regenerate a normal scalp hair phenotype are used. This is the first study comparing treatment efficacy response and resistance using standardized continuous outcomes.
Objective: To systematically compare the relative efficacy of treatments used for terminal hair (TH) regrowth in women and men with AGA.
Oral fluids (OFs) represent a cost effective and reliable tool for surveillance purposes, mostly regarding viruses. In the present study, we evaluated the suitability of OFs for surveillance purposes concerning () infections in fattening pigs under field conditions. OFs were examined with an Apx-toxin real-time PCR that detects the genes encoding for Apx I-, Apx III-, and Apx IV-toxin.
View Article and Find Full Text PDFIntroduction: ALRV5XR treatment of androgenetic alopecia (AGA) and telogen effluvium (TE) has early evidence of regenerating a normal scalp hair phenotype in both sexes.
Design: We performed two 24-week double-blinded placebo-controlled comparison trials, one in each sex, on the ALRV5XR treatment effect on hair regeneration, in AGA and TE, in 92 AGA subjects (24 also had TE). Forty-six women (age 24-64 years) and 46 men (age 22-63 years) were randomized 1:1 to either ALRV5XR or placebo regimens (one b.
In order to restore the regeneration capacity of large-size vascularized tissue defects, innovative biomaterial concepts are required. Vascular endothelial growth factor (VEGF) is a key factor of angiogenesis interacting with sulfated glycosaminoglycans (sGAG) within the extracellular matrix. As this interplay mainly controls and directs the biological activity of VEGF, we used chemically modified sGAG derivatives to evaluate the structural requirements of sGAG for controlling and tuning VEGF function and to translate these findings into the design of biomaterials.
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