Publications by authors named "K Fechner"
The management of retrorectal tumors - a single-center analysis of 21 cases and overview of the literature.
Langenbecks Arch Surg
September 2024
Aim: Retrorectal tumors are rare and heterogeneous. They are often asymptomatic or present with nonspecific symptoms, making management challenging. This study examines the diagnosis and treatment of retrorectal tumors.
View Article and Find Full Text PDFBackground: Local ablative therapies (LAT) are increasingly used in patients with metastatic soft tissue sarcoma (STS), yet evidence-based standards are lacking. This study aimed to assess the impact of LAT on survival of metastatic STS patients and to identify prognostic factors.
Methods: In this retrospective multicenter study, 246 STS patients with metastatic disease who underwent LAT on tumor board recommendation between 2017 and 2021 were analyzed.
Primary care gynecologists are increasingly integrated into the care of patients with hereditary breast and ovarian cancer (HBOC) risks. These physicians should not only have basic genetic knowledge; they should also feel able to sensitively address an increased HBOC risk and deal with emotional, stressful situations in this context. Our project aimed at developing a training module, 'iKNOWgynetics', addressing psychosocial challenges in the context of HBOC care for primary care gynecologists.
View Article and Find Full Text PDFArticle Synopsis
- Dermatitis herpetiformis (DH) is a rare skin condition triggered by gluten, characterized by the presence of specific IgA autoantibodies against proteins like endomysium and transglutaminase.
- An international study analyzed serum samples from 242 DH patients at diagnosis, using various methods including indirect immunofluorescence on monkey oesophagus and ELISA tests for specific autoantibodies.
- The findings showed that IgA antibodies detected via indirect immunofluorescence had the highest reactivity and diagnostic accuracy, indicating a strong link between these autoantibodies and DH, which can be further improved with additional testing.
Aim: The sequence of radiotherapy and resection in patients with soft tissue sarcomas is usually discussed on an individual basis. Better understanding of potential differences of health-related quality of life (QoL) between patients undergoing adjuvant (ART) versus neoadjuvant radiotherapy (NART) is therefore helpful for clinical decision making.
Methods: Adult sarcoma patients from 39 hospitals completed the European Organisation for Research and Treatment of Cancer Quality of Life Core Questionnaire (EORTC QLQ-C30).