Publications by authors named "K Fabianowska-Majewska"
Article Synopsis
- The study explored how different metallic microfillers (spherical silver, spherical copper, and dendritic copper) affect the ability of polyamide 12 (PA12) to prevent microorganism growth on surfaces made using laser-based powder bed fusion technology, targeting applications in hospitals where disinfection is common.
- Composite powders were created with varying concentrations of microfillers and tested against common hospital pathogens, along with assessing their safety using human cell lines.
- While the addition of copper or silver improved antibacterial properties, it also highlighted varying levels of toxicity to human cells, suggesting the need for more research to confirm their safety for use in medical environments.
Essential Oils (EOs) are currently being researched as potential antibiofilm agents to combat infections related to chronic wound biofilms. As documented in the literature, EOs' in vitro antibacterial properties are often assessed using standard microbiological media and conditions that do not accurately reflect the actual environment of a chronic wound. To address this issue, In vitro Wound Milieu (IVWM) medium, which closely resembles the environment of a chronic wound, was applied for culturing S.
View Article and Find Full Text PDFCancer diseases are a leading cause of death worldwide. Therefore, it is pivotal to search for bioactive dietary compounds that can avert tumor development. A diet rich in vegetables, including legumes, provides chemopreventive substances, which have the potential to prevent many diseases, including cancer.
View Article and Find Full Text PDFOne of the most systematically studied bioactive nutraceuticals for its benefits in the management of various diseases is the turmeric-derived compounds: curcumin. Turmeric obtained from the rhizome of a perennial herb L. is a condiment commonly used in our diet.
View Article and Find Full Text PDFClofarabine‑phytochemical combination exposures in CML cells inhibit DNA methylation machinery, upregulate tumor suppressor genes and promote caspase‑dependent apoptosis.
Mol Med Rep
October 2019
Clofarabine (2‑chloro‑2'‑fluoro‑2'‑deoxyarabinosyladenine, CIF), a second‑generation 2'‑deoxyadenosine analog, possesses a variety of anti‑cancer activities, including the capacity to modulate DNA methylation marks. Bioactive nutrients, including resveratrol (RSV) and all‑trans retinoic acid (ATRA) have been indicated to regulate epigenetic machinery in malignant cells. The purpose of the current study was to evaluate whether the tested phytochemicals, RSV or ATRA, can improve the therapeutic epigenetic effects of CIF in chronic myeloid leukemia (CML) cells.
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