Determining patient activity goals and their fulfillment following total knee arthroplasty: Findings from the prospective, observational SuPeR Knee study.

Background: Dissatisfaction with Total Knee Arthroplasty (TKA) surgical outcomes remains between 10-20% and is associated with higher levels of societal costs. Expectations regarding post-surgical outcomes is considered as one of the major factors influencing satisfaction, however, there are no standardised methods for assessing patient's expectations regarding activities to be achieved following surgery.

Objectives: The aims of this study were to identify patient expectations relating to activities of importance following TKA and to describe goal fulfillment at 3 months post-TKA.

High Impedance Microstrip Resonators and Transceiver Arrays for Ultrahigh Field 10.5T MR Imaging.

Multichannel transceiver coil arrays are needed to enable parallel imaging and B1 manipulation in ultrahigh field MR imaging and spectroscopy. However, the design of such transceiver coils and coil arrays often faces technical challenges in achieving the required high operating frequency at the ultrahigh fields and sufficient electromagnetic (EM) decoupling between resonant elements. In this work, we propose a high impedance microstrip transmission line resonator (HIMTL) technique that has unique high frequency capability and adequate EM decoupling without the use of dedicated decoupling circuits.

Social context modulates active avoidance: Contributions of the anterior cingulate cortex in male and female rats.

Actively avoiding danger is necessary for survival. Most research on active avoidance has focused on the behavioral and neurobiological processes when individuals learn to avoid alone, within a solitary context. Therefore, little is known about how social context affects active avoidance.

Inborn errors of immunity reveal molecular requirements for generation and maintenance of human CD4 IL-9-expressing cells.

Background: CD4 T cells play essential roles in adaptive immunity. Distinct CD4 T-cell subsets-T1, T2, T17, T22, T follicular helper, and regulatory T cells-have been identified, and their contributions to host defense and immune regulation are increasingly well defined. IL-9-producing T9 cells were first described in 2008 and appear to play both protective and pathogenic roles in human immunity.