Objective: The study aims to assess the effect of intrauterine metformin exposure on offspring adiposity measures in childhood.
Design: Systematic review and meta-analysis.
Data Sources: Medline, Embase and Cochrane Central were searched from inception to 4 October 2024.
Metabolic dysfunction-associated steatohepatitis (MASH), formerly known as nonalcoholic steatohepatitis (MASH), is a major risk factor for cirrhosis and hepatocellular carcinoma (HCC) and a leading cause of liver transplantation. MASH is caused by an accumulation of toxic fat molecules in the hepatocyte which leads to inflammation and fibrosis. Inadequate human "MASH in a dish" models have limited our advances in understanding MASH pathogenesis and in drug discovery.
View Article and Find Full Text PDFWe report two cases of recurrent malaria in U.S. travelers returning from Africa (Ghana and Central African Republic) despite a full course of artemether-lumefantrine (AL).
View Article and Find Full Text PDFInt J Sports Phys Ther
January 2025
Background: Kettlebell (KB) swing exercises, whether performed using shoulder height (SHS) or overhead (OHS) swing variations in therapeutic or strength and conditioning settings, are posterior chain dominant exercises that require hip extension contributions when performed correctly.
Purpose/ Hypothesis: The primary purpose of this study was to evaluate the effect of swing style (SHS, OHS) and KB mass on hip extension kinematics and kinetics in young adult females. A secondary purpose was to determine the effects of swing style and KB mass on the forces applied to the total body center of mass and KB.