Publications by authors named "K F Khafizov"
Article Synopsis
- * Hepatitis A showed increasing prevalence with age, while hepatitis E and B were detected at rates of 4.1% and 4.6%, respectively, with no cases of HBV in those under 30, highlighting a successful vaccination program.
- * The study found that while HBV strains were local and date back centuries, hepatitis C strains were introduced from other regions in the late 20th century, indicating a need for better screening and care for viral hepatitis in these populations.
Local recurrence after surgical and therapeutic treatment remains a significant clinical problem in oncology. Recurrence may be due to imperfections in existing therapies, particularly chemotherapy. To improve antitumor activity and prevent local cancer recurrence while keeping toxicity at acceptable levels, we have developed and demonstrated a biodegradable local chemotherapy platform that provides controlled and prolonged drug release.
View Article and Find Full Text PDFIntroduction: Puumala virus (family , genus ) is distributed in most regions of the European part of Russia. However, information about its genetic variants circulating on the territory of the Central Federal District is extremely scarce.
Materials And Methods: Rodents' tissue samples were tested after reverse transcription by PCR for the presence of hantaviral RNA.
Introduction: Bastroviruses were discovered in the Netherlands in 2016 in human stool samples and show partial genetic similarities to astroviruses and hepatitis E viruses. Their association with disease onset has not yet been established.
Materials And Methods: Metagenomic sequencing of fecal samples of bats collected in the Russian Federation in 2023 was performed.
Next-generation sequencing technologies have revolutionized the field of virology by enabling the reading of complete viral genomes, extensive metagenomic studies, and the identification of novel viral pathogens. Although metagenomic sequencing has the advantage of not requiring specific probes or primers, it faces significant challenges in analyzing data and identifying novel viruses. Traditional bioinformatics tools for sequence identification mainly depend on homology-based strategies, which may not allow the detection of a virus significantly different from known variants due to the extensive genetic diversity and rapid evolution of viruses.
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