Publications by authors named "K F J Spijkers"
Objectives: Antibiotic treatment for bone and joint infections generally lasts for 6 weeks or longer. Linezolid may be a good option for treating bone and joint infections, but there is an increased risk of potential serious adverse drug events (ADEs) when used for more than 28 days. The aim of this study was to obtain detailed information on the type and time to occurrence of the patient-reported ADEs, the dynamics of haematopoiesis over time, and the reasons for early discontinuation of linezolid when used for an intended maximum duration of 12 weeks.
View Article and Find Full Text PDFDuring the COVID-19 pandemic the question arises if laparoscopy, as an aerosol forming procedure, poses a potential risk for viral transmission of SARS-CoV-2 to healthcare workers. A literature search was conducted using PubMed, Embase and MEDLINE. Articles reporting information regarding COVID-19 or other relevant viruses and laparoscopy, surgical smoke, aerosols and viral transmission were included.
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- The study tested the effectiveness of benzoyl peroxide (BPO) in reducing Cutibacterium acnes on the shoulder skin, as this bacterium is a common cause of infections after shoulder surgery.
- Participants aged 40-80, who had C acnes, were divided into two groups: one received BPO and the other a placebo, with swabs taken after five applications.
- Results showed a significant reduction of C acnes in the BPO group (20% presence) compared to the placebo group (71.4% presence), indicating that BPO could help lower the risk of infections after shoulder surgery.
Article Synopsis
- The study aimed to evaluate the quality of patient-reported medical information in the Dutch Biologic Monitor and assess the representativeness of participants involved in the research.
- Data from 550 adult patients using biologic DMARDs were analyzed, revealing a 95.8% accuracy in reporting the correct medication and strong agreement with electronic health records, particularly for treatment indications and combination therapies.
- The findings suggest that the Dutch Biologic Monitor is a reliable tool for collecting patient-reported information, as it aligns well with existing records and reflects the demographic characteristics of the broader population.