[Histopathologic characteristics and clinical behavior of superficial bladder tumors].

The authors analyse the histopathological features and clinical behaviour of 325 superficial (Ta, T1) tumours of 232 patients with bladder cancer. Each of the tumours was treated by TUR using differentiating resection technique and multiple cold biopsy was performed in 197 patients. The recurrence and progression of superficial tumours are examined during the 3-192 months follow up time.

[Radical transurethral resection of bladder tumors].

During the last ten years the authors treated 462 bladder tumors of 319 patients in the expectation of radicality. On the basis of histopathological examination following TURs with differenciating technique the tumor-removing proved true in the cases of 360 tumors (78%). The first TUR was radical only in 65% of the tumors, in 10% the second, in 2% the third and in 1% the fourth intervention resulted full radicality.

[Significance of seemingly intact urothelium in patients with bladder cancer].

During 9 years (from 1979 to 1988) the authors performed 412 multiple cold biopsies taken from 9 different points of the cancerous bladder in 263 patients. In 42 per cent of the patients the hystopathological examination of biopsy materials discovered dysplasia, carcinoma in situ or tumor of the grossly normal urothelium. The frequency of these proliferative lesions is closely connected with number, configuration, grading and depth of infiltration of overt bladder tumor.