[Method of automated cytomorphological analysis for classifying leukocytes by their stage of destruction].

Destruction of human peripheral blood leukocytes by toxins has been studied with the aid of an automatic microimage analyzer the "Morphoquant". The most informative parameters which define destruction stages have been revealed: the area and number of fragments of nucleus images and their distance to the nucleus centre under different levels of the optical threshold. Software for morphological analysis of leukocytes has been developed in addition to their classification using four destruction stages.

[Patterns in the body's immune response to administration of El Tor vibrio cholera toxin to experimental animals].

A study was made of some regularities attending the mechanisms of antibody production in the organism of experimental animals after the administration of El Tor cholera vibrio toxin. As revealed, the indices of the immune response depended on the chosen model, the method of its determination, the method of administration and the amount of the toxin administered. Dynamics of the primary and secondary responses of the immunocompetent cells of mouse spleen was determined.