Publications by authors named "K F Doerner"

Safe and secure vehicle routing problems refer to the transportation of dangerous (e.g., flammable liquids) or valuable goods (e.

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A complex microbial community in the gut may prevent the colonization of enteric pathogens such as . Some individual or a combination of species in the gut may confer colonization resistance against . To gain a better understanding of the colonization resistance against , we isolated a library of 1,300 bacterial strains from feral chicken gut microbiota which represented a total of 51 species.

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Liquid sample delivery systems are used extensively for serial femtosecond crystallography at X-ray free-electron lasers (XFELs). However, misalignment of the liquid jet and the XFEL beam leads to the X-rays either partially or completely missing the sample, resulting in sample wastage and a loss of experiment time. Implemented here is an algorithm to analyse optical images using machine vision to determine whether there is overlap of the X-ray beam and liquid jet.

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Article Synopsis
  • The study focuses on how enzymes interact with substrates or ligands in real time, specifically observing the first phase of the reaction using advanced imaging techniques.* -
  • Researchers utilized the European XFEL (EuXFEL) to achieve near-atomic resolution and track ceftriaxone binding to β-lactamase, combining high repetition rates and mix-and-inject technology for time-resolved measurements.* -
  • The findings included calculating a diffusion coefficient to understand concentrations in enzyme crystals over time and describing the binding of the inhibitor sulbactam, showcasing the potential of EuXFEL for biomedical research.*
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In late 2019 a new coronavirus disease (COVID-19) emerged, causing a global pandemic within only a few weeks. A crucial factor in the public health response to pandemics is achieving a short turnaround time between a potential case becoming known, specimen collection and availability of a test result. In this article we address a logistics problem that arises in the context of testing potential cases.

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