Publications by authors named "K Ezaki"

Article Synopsis
  • * A 2022 survey revealed that while many view gene-edited foods as unnatural, some consumers appreciate their benefits, highlighting a complex relationship between acceptance and concerns about artificiality.
  • * The study emphasizes the importance of understanding not just the vocal opinions in surveys, but also the views of those who feel indifferent or choose not to express their thoughts, indicating a deeper societal complexity that needs more exploration.
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Article Synopsis
  • A 76-year-old woman was hospitalized due to chest and back pain, leading to the discovery of a 62-mm giant coronary artery aneurysm originating from the left main trunk (LMT).
  • Urgent surgery removed the aneurysm and a coronary artery-pulmonary artery fistula, with a focus on reconstructing the LMT due to a defect less than 2 cm.
  • The surgery was successful, with anatomical reconstruction using a short segment of the great saphenous vein, and the patient was discharged without complications.
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During leaf development, the timing of transition from cell proliferation to expansion is an important factor in determining the final organ size. However, the regulatory system involved in this transition remains less understood. To get an insight into this system, we investigated the compensation phenomenon, in which the cell number decreases while the cell size increases in organs with determinate growth.

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The nuclear receptor peroxisome proliferator-activated receptor α (PPARα) is a transcription factor that controls the transcription of genes responsible for fatty acid metabolism. We have recently reported a possible drug-drug interaction mechanism via the interaction of PPARα with the xenobiotic nuclear receptor constitutive androstane receptor (CAR). Drug-activated CAR competes with the transcriptional coactivator against PPARα and prevents PPARα-mediated lipid metabolism.

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