Publications by authors named "K Elkie Peebles"
Article Synopsis
- - Women-initiated HIV-1 prevention methods, like vaginal microbicides, have shown limited effectiveness in clinical trials, with hypotheses suggesting that efficacy dilution is a key issue.
- - A microsimulation model analyzed the MTN-020/ASPIRE trial of a dapivirine vaginal ring, identifying factors causing efficacy dilution, such as risk variability, product non-adherence, and differences in sexual behavior between study groups.
- - The study found that heterogeneity in risk was the primary contributor to efficacy dilution (42%), highlighting the need for better trial designs in future research to address this bias.
The aims of this quality improvement programme were to enable providers of mental health in-patient services for children and young people in England to review their prescribing practice alongside the views and experiences of children, young people and their parent carers. Three online tools were developed. First was a medication census tool to be completed by provider clinicians to capture prescribing practices around psychotropic medication.
View Article and Find Full Text PDFIntroduction: Molnupiravir (MOV) is an oral antiviral for the treatment of individuals with mild-to-moderate COVID-19 and at high risk of progression to severe disease. Our objective was to conduct a systematic literature review (SLR) of evidence on the effectiveness of MOV in reducing the risk of severe COVID-19 outcomes in real-world outpatient settings.
Methods: The SLR was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines and using pre-determined population, intervention, comparison, outcome, time, and study design inclusion criteria.