Metabolic tug-of-war: Microbial metabolism shapes colonization resistance against enteric pathogens.

A widely recognized benefit of gut microbiota is that it provides colonization resistance against enteric pathogens. The gut microbiota and their products can protect the host from invading microbes directly via microbe-pathogen interactions and indirectly by host-microbiota interactions, which regulate immune system function. In contrast, enteric pathogens have evolved mechanisms to utilize microbiota-derived metabolites to overcome colonization resistance and increase their pathogenic potential.

Meet the authors: Katerina Jones, Camila Bernardo de Brito, and Mariana Xavier Byndloss.

In an interview with Samantha Nelson, a scientific editor of Cell Chemical Biology, the authors of the review entitled "Metabolic tug-o-war: Microbial metabolism shapes colonization resistance against enteric pathogens" share their perspectives on the field and their lives as scientists.

Using a participatory approach to identify priorities to advance LHS implementation at an academic medical center.

Introduction: Like many other academic medical centers, the University of Alabama at Birmingham (UAB) aspires to adopt learning health system (LHS) principles and practices more fully. Applying LHS principles establishes a culture where clinical and operational practices constantly generate questions and leverage information technology (IT) and methodological expertise to facilitate systematic evaluation of care delivery, health outcomes, and the effects of improvement initiatives. Despite the potential benefits, differences in priorities, timelines, and expectations spanning an academic medical center's clinical care, administrative operations, and research arms create barriers to adopting and implementing an LHS.

How are the Spiritual Resources and Needs of Mental Health Consumers Identified and Documented by Staff upon Admission to an Australian Mental Health Service? A Mixed Methods Study.

This study investigated how the spiritual resources and needs of Australian mental health consumers are identified by staff during admission at an inner-city acute care hospital. A mixed-methods study was conducted incorporating an audit of medical records (n = 205), and a staff focus group (n = 6). The results revealed that information collected during admission is often limited to factors such as medical and social history.

Impact of Gender Identity Field in the Veterans Health Administration Electronic Health Record, 2016‒2023.

To distinguish differences in physical and mental health between transgender and gender-diverse (TGD) veterans identified via diagnostic codes, self-identification, and their combination. We used sociodemographic characteristics and physical and mental health diagnoses for TGD veterans receiving care in Veterans Health Administration (VHA). Among the cohort of 12 745 TGD veterans, 69.