Publications by authors named "K Eildermann"
Article Synopsis
- The study aimed to evaluate how well different types of vascular patches (bovine, equine, and human autologous pericardium) are accepted by the body when used for repairing congenital heart defects.
- Various histological techniques were employed to analyze tissue composition and assess biocompatibility, scoring factors like inflammation and degradation.
- Results showed that human autologous patches had better biocompatibility compared to tissue-engineered types, with bovine patches demonstrating significant calcifications and equine patches showing more foreign body reactions.
: Sex-specific differences in heart disease outcomes are influenced by the levels of the steroid hormones, estrogen and testosterone. While the roles of estrogen receptors in cardiac disease are well-studied in animals and humans, respective research on androgen receptors (AR) is limited. Here we investigate AR protein and mRNA expression in human myocardium of various cardiac diseases.
View Article and Find Full Text PDFAims: State-of-the-art pacemaker implantation technique in infants and small children consists of pace/sense electrodes attached to the epicardium and a pulse generator in the abdominal wall with a significant rate of dysfunction during growth, mostly attributable to lead failure. In order to overcome lead-related problems, feasibility of epicardial implantation of a leadless pacemaker at the left ventricular apex in a growing animal model was studied.
Methods And Results: Ten lambs (median body weight 26.
Background: Ventricular pacing can cause myocardial dysfunction, but how lead anchoring to the myocardium affects function has not been studied.
Objective: The purpose of this study was to evaluate patterns of regional and global ventricular function in patients with a ventricular lead using cine cardiac computed tomography (CCT) and histology.
Methods: This was a single-center retrospective study with 2 groups of patients with a ventricular lead: (1) those who underwent cine CCT from September 2020 to June 2021 and (2) those whose cardiac specimen was analyzed histologically.
Background: Stenting of stenotic right ventricular outflow tract is a palliative measure for severely impaired small babies with Tetralogy of Fallot or similar pathologies. Little is known about the histopathological fate of the stents in the right ventricular outflow tract.
Methods: Eight samples of surgically removed right ventricular outflow tract stents were histologically analysed according to a predefined protocol.