Publications by authors named "K Economy"

Background: Electrocardiograms (EKGs) are routinely performed in pregnant patients with pre-existing cardiovascular disease. However, in pregnant patients with congenital heart disease (CHD), EKG changes during gestation have not been explored.

Methods: We performed a retrospective study of pregnant patients with CHD enrolled in the STORCC initiative.

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Background: Preeclampsia is a hypertensive disorder of pregnancy characterized by systemic endothelial dysfunction. The pathophysiology of preeclampsia remains incompletely understood. This study used human venous endothelial cell (EC) transcriptional profiling to investigate potential novel mechanisms underlying EC dysfunction in preeclampsia.

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We identified 347 pregnancies in patients with beta thalassemia minor. Hemoglobin was below 9 g/dL in 31% during third trimester and 7.6% at delivery.

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Article Synopsis
  • Maternal mortality in the U.S. is a significant public health issue, with cardiovascular disease (CVD) being a leading cause of related deaths and health complications.
  • Labor and delivery pose heightened risks for pregnant individuals with CVD, yet there is varied approach to management due to a lack of high-quality randomized studies.
  • To address this, a panel of experts including cardiologists and obstetricians has come together to create practical guidelines for managing labor and delivery for high-risk patients with CVD, covering aspects like delivery method, timing, and use of medical devices.
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