Publications by authors named "K Ebihara"
Article Synopsis
- Mechanical thrombectomy (MT) is effective for acute basilar artery occlusion (ABAO), but many patients still experience poor outcomes, prompting the need for better pre-treatment assessments.
- A study of 144 ABAO patients from 10 hospitals revealed that 37.5% had miserable outcomes, defined as a modified Rankin Scale (mRS) score of 5-6 three months post-treatment.
- Key factors linked to these poor outcomes included high NIHSS scores and the size of brainstem infarction, with specific cutoff values that could help clinicians decide if MT is appropriate for a patient.
Article Synopsis
- The study explores the link between nutritional status and mortality in elderly patients with idiopathic pulmonary fibrosis (IPF), focusing on those aged 65 and older who attended a rehabilitation department over seven years.
- An analysis of 170 patients found that while severe malnutrition was absent, moderate malnutrition indicated a significantly higher risk of mortality compared to normal and mild groups, highlighting the importance of the CONUT score.
- Multivariate analysis identified factors such as GAP stage, mMRC scale, and CONUT score as significant predictors of all-cause mortality, underscoring the need for nutritional assessment in managing IPF patients.
Aims/introduction: Insulin resistance syndrome and lipoatrophic diabetes are rare conditions characterized by the development of treatment-refractory diabetes with severe insulin resistance. We recently conducted a 24 week, multicenter, single-arm trial (EMPIRE-01) that demonstrated a certain level of effectiveness and safety of empagliflozin for these conditions. To evaluate treatment safety over a longer period, we have now performed an additional 28 week trial (EMPIRE-02) that followed on from EMPIRE-01.
View Article and Find Full Text PDFThe steroid hormone ecdysone is essential for the reproduction and survival of insects. The hormone is synthesized from dietary sterols such as cholesterol, yielding ecdysone in a series of consecutive enzymatic reactions. In the insect orders Lepidoptera and Diptera a glutathione transferase called Noppera-bo (Nobo) plays an essential, but biochemically uncharacterized, role in ecdysteroid biosynthesis.
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