Low-dose naltrexone in the treatment of fibromyalgia: A systematic review and narrative synthesis.

Method: A systematic literature search was conducted using the key words 'naltrexone', 'fibromyalgia', 'fibrositis', 'chronic pain' and 'neurogenic inflammation'.

Results: Manual exclusion led to the identification of 21 papers, with only five prospective controlled trials of low sample size.

Discussion: Low-dose naltrexone may be an effective and safe pharmacotherapy for patients with fibromyalgia.

A Digital Coaching Intervention for Cancer Survivors With Job Loss: Retrospective Study.

Background: Returning to work is a key unmet need for working-age cancer survivors.

Objective: This study sought to evaluate return-to-work outcomes of a multidisciplinary intervention provided as routine employee support.

Methods: In a retrospective cohort analysis, patients with cancer and more than 3 months of absence from work were provided with an intervention consisting of digital resources and calls with a health coach.

Genomic Sequencing Procedure Microcosting Analysis and Health Economic Cost-Impact Analysis: A Report of the Association for Molecular Pathology.

The increasing use of advanced nucleic acid sequencing technologies for clinical diagnostics and therapeutics has made vital understanding the costs of performing these procedures and their value to patients, providers, and payers. The Association for Molecular Pathology invested in a cost and value analysis of specific genomic sequencing procedures (GSPs) newly coded by the American Medical Association Current Procedural Terminology Editorial Panel. Cost data and work effort, including the development and use of data analysis pipelines, were gathered from representative laboratories currently performing these GSPs.