Publications by authors named "K E Squires"
Very few people have the opportunity to witness a post-mortem first-hand in a mortuary environment. These spaces are typically reserved for those in the medical profession, including doctors in training. However, students enrolled on other programmes may go on to future careers that involve interacting with deceased individuals.
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- The Capuchin Catacombs in Palermo have housed mummified remains of non-adults since the 17th century, but research on these individuals from 1787-1880 CE is limited.
- This study examined 43 mummified non-adults to assess their health, causes of death, and funerary practices, utilizing portable X-ray technology for insights into their conditions and mummification.
- Findings show that funerary rites were influenced by the deceased's family's wealth rather than health status, with individuals often dying from short-term illnesses and displaying various artifacts related to mummification and conservation.
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- - The study investigates the role of heteroresistance in cefiderocol treatment failure among patients with carbapenem-resistant Acinetobacter baumannii (CRAb) infections, finding a significant portion (59%) of the isolates had heteroresistance, particularly higher in Italy compared to the USA.
- - Patients with cefiderocol-heteroresistant strains had worse clinical outcomes, with 81% experiencing treatment failure, compared to 55% for those with susceptible strains, and higher minimum inhibitory concentrations (MICs) were linked to increased failure rates.
- - Whole-genome sequencing revealed a genetic mutation in some heteroresistant isolates, supporting the idea that both higher MICs and the presence of resistant subpopulations contribute to
Malnutrition rates in Advanced Liver Disease (ALD) are significantly higher than those in well-compensated liver disease. In addition to its physiological impact, malnutrition is detrimental for quality of life and social, emotional, and psychological well-being. Studies within oncology and renal supportive care have identified the influence of non-physiological factors on malnutrition risk.
View Article and Find Full Text PDFImmersed boundary methods have seen an enormous increase in popularity over the past two decades, especially for problems involving complex moving/deforming boundaries. In most cases, the boundary conditions on the immersed body are enforced via forcing functions in the momentum equations, which in the case of fractional step methods may be problematic due to: i) creation of slip-errors resulting from the lack of explicitly enforcing boundary conditions on the (pseudo-)pressure on the immersed body; ii) coupling of the solution in the fluid and solid domains via the Poisson equation. Examples of fractional-step formulations that simultaneously enforce velocity and pressure boundary conditions have also been developed, but in most cases the standard Poisson equation is replaced by a more complex system which requires expensive iterative solvers.
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