Publications by authors named "K E Nachman"

International pet travel and commercial operations have increased animal disease importation risks, including for Leishmania infantum, a deadly parasite of humans and domestic dogs. Collaborating as an interdisciplinary working group, we developed an operational tool for veterinary and public health practitioners to assess and manage L. infantum risk in dogs imported to the United States.

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Background: Time Activity Data (TAD) describe the timing, duration, and/or frequency of human activities. Given that activity dictates the rate of contact a person has with an environmental agent, activity data can be used to derive rigorous estimates of exposure. TAD has been used to support exposure estimation in a variety of contexts, although there has been no systematic characterization of how TAD has been collected for environmental health applications.

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Article Synopsis
  • * Novel techniques like nontargeted analysis (NTA) can identify a wide range of organic contaminants, generating extensive data that can help assess environmental and human health risks.
  • * A study using NTA and the U.S. EPA's Cheminformatics Hazard Comparison Module identified and classified 451 features in biosolids, prioritizing compounds like p-cresol and triclocarban for future environmental impact studies.
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Article Synopsis
  • Ethylene oxide (EtO) is a volatile organic compound and carcinogen, with limited reliable data on its ambient concentrations near production facilities, raising exposure concerns.
  • In February 2023, sensitive mobile measurements in southeastern Louisiana showed that 75% of sampled areas had EtO levels above the threshold associated with a 1-in-a-million cancer risk, with some locations exceeding levels indicating a 1-in-1,000 risk.
  • This study revealed higher EtO concentrations than previous EPA estimates and highlights the need for improved monitoring methods to assess exposure risks in industrial areas.
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Background: Soil is an understudied and underregulated pathway of chemical exposure, particularly for agricultural workers who cultivate food in soils. Little is known about how agricultural workers spend their time and how they may contact soil while growing food. Exposure factors are behavioral and environmental variables used in exposure estimation.

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