Publications by authors named "K E Mullin"
Article Synopsis
- Alzheimer's disease is a leading form of dementia in older adults, and early detection is crucial for effective intervention since its effects can begin decades before symptoms show.
- The study utilized advanced machine learning techniques to create models predicting Alzheimer's status and onset age, analyzing a range of biological and medical data from UK Biobank, with significant emphasis on the importance of specific proteins.
- Notable findings include that GFAP and CXCL17 proteins are strong predictors of Alzheimer's, while genomics and proteomics provided the most valuable information in predicting disease status, although expanding the dataset with "AD-by-proxy" cases didn't enhance prediction accuracy.
Objective: Shared decision-making (SDM) between parents facing extremely preterm delivery and the medical team is recommended to develop the best course of action for neonatal care. We aimed to describe the creation and testing of a literature-based checklist to assess SDM practices for consultation with parents facing extremely preterm delivery.
Study Design: The checklist of SDM counseling behaviors was created after literature review and with expert consensus.
Molecular qubits are a promising platform for future quantum information science technologies; however, to find success in novel devices requires that the molecules exhibit long spin relaxation times. Understanding and optimizing these relaxation times has been shown to be challenging and much experimental work has been done to understand how various chemical features of the molecular qubit influence relaxation times. Here we have curated a data set of relaxation times of metal complex molecular qubits and formulated systems design charts to provide a hierarchical organization of how chemical variables affect relaxation times known physical processes.
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- Alzheimer's disease (AD) is the most common form of dementia, and while many genetic factors have been found, research has mostly focused on people of European descent.
- This study analyzed whole genome sequencing data from a diverse group of participants (about 49,000 AD cases and 383,000 controls) to identify new genetic loci associated with AD.
- The researchers discovered 16 novel loci linked to clinically-diagnosed AD and AD-by-proxy, emphasizing the need for more diverse studies in genetic research.
Studies in evolution, ecology and conservation are increasingly based on genetic and genomic data. With increased focus on molecular approaches, ethical concerns about destructive or more invasive techniques need to be considered, with a push for minimally invasive sampling to be optimised. Buccal swabs have been increasingly used to collect DNA in a number of taxa, including amphibians.
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