Paradoxical pyoderma gangrenosum secondary to adalimumab successfully treated with methotrexate: a case report.

Pyoderma gangrenosum (PG) is a rare inflammatory skin disorder, categorized under neutrophilic dermatoses. It can be idiopathic or associated with underlying conditions like inflammatory bowel disease, autoimmune diseases, and certain cancers. Some medications, including TNF-alpha inhibitors like adalimumab, can also induce this paradoxical reaction.

Trends in allied dental education: an analysis of the past and a look to the future.

Allied dental healthcare providers have been an integral part of the dental team since the turn of the 19th century. Like dental education, allied dental education's history includes a transition from apprenticeships and proprietary school settings to dental schools and community and technical colleges. There are currently 258 dental assisting programs, 255 dental hygiene programs, and 28 dental laboratory technology programs according to the American Dental Association's Commission on Dental Accreditation.

Respiratory response to a decrease in velopharyngeal resistance.

Individuals with congenital velopharyngeal impairment generally maintain adequate levels of intraoral pressures during consonant production by increasing respiratory effort. The purpose of the present study was to determine if normal individuals respond to a decrease in velopharyngeal resistance in a similar way. The velar mechanism was perturbed by having subjects voluntarily lower the soft palate during a series of words involving plosive consonants.

The speech regulating system: temporal and aerodynamic responses to velopharyngeal inadequacy.

Temporal and respiratory responses to a loss of velar resistance were measured in 107 subjects demonstrating varying degrees of velopharyngeal inadequacy. The subject data were compared to data generated by a mechanical model representing a passive system. The pressure-flow technique was used to estimate velopharyngeal orifice size and measure respiratory and temporal characteristics of aerodynamic events associated with the production of the nasal-plosive blend /mp/ in the word "hamper".

Effects of velar resistance on speech aerodynamics.

The level of intelligibility attained by speakers with cleft palate reflects not only the ability to achieve adequate velopharyngeal closure but other complex variables as well. When closure is inadequate, performance is influenced by compensatory responses of the tongue, vocal folds, respiratory muscles and nasal valve. The purpose of the present study was to determine how a loss of velar resistance associated with velopharyngeal inadequacy affects speech pressures and airflow.