Publications by authors named "K E Lord"

Background: Hypertension is the leading modifiable risk factor for premature death globally despite the existence of evidence-based and cost-effective treatments. Medication nonadherence is cited as the main cause of treatment failure for hypertension. In Peru, adherence to anti-hypertensive medications of individuals with both hypertension and type 2 diabetes (T2D) is not well studied.

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Hypoketotic hypoglycemia due to dysregulated insulin secretion is the most common cause of persistent hypoglycemia in children. However, this type of hypoglycemia can also result from defects in the insulin signaling pathway. Distinguishing between the two is important for informing treatment decisions.

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Dogs have played an outsized role in the field of behavioral genetics since its earliest days. Their unique evolutionary history and ubiquity in the modern world make them a potentially powerful model system for discovering how genetic changes lead to changes in behavior. Genomic technology has supercharged this potential by enabling scientists to sequence the DNA of thousands of dogs and test for correlations with behavioral traits.

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Article Synopsis
  • - The study investigates children with congenital hyperinsulinism (HI) who do not respond to diazoxide and lack detectable mutations in their blood, focusing on potential hidden genetic changes in pancreatic tissue.
  • - Through next-generation sequencing on pancreatic specimens from 10 children, four unique GCK mutations were found at low levels, indicating that these mutations may be responsible for their HI, despite not being detectable in their blood samples.
  • - The findings suggest that post-zygotic somatic mutations in the GCK gene contribute to certain cases of non-focal diazoxide-unresponsive hyperinsulinism, shedding light on the complexity of genetic causes in this condition.
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Language is processed incrementally, with addressees considering multiple candidate interpretations as speech unfolds, supporting the retention of these candidate interpretations in memory. For example, after interpreting the utterance, "Click on the striped bag", listeners exhibit better memory for non-mentioned items in the context that were temporarily consistent with what was said (e.g.

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