Publications by authors named "K E Larsen"
We describe the design and performance of a magnetic bottle electron spectrometer (MBES) for high-energy electron spectroscopy. Our design features a 2 m long electron drift tube and electrostatic retardation lens, achieving sub-electronvolt (eV) electron kinetic energy resolution for high energy (several hundred eV) electrons with a close to 4π collection solid angle. A segmented anode electron detector enables the simultaneous collection of photoelectron spectra in high resolution and high collection efficiency modes.
View Article and Find Full Text PDFImportance: New pharmacotherapy options are needed for posttraumatic stress disorder (PTSD).
Objective: To investigate the efficacy, safety, and tolerability of brexpiprazole and sertraline combination treatment (brexpiprazole + sertraline) compared with sertraline + placebo for PTSD.
Design, Setting, And Participants: This was a parallel-design, double-blind, randomized clinical trial conducted from October 2019 to August 2023.
This case report presents a ten-year-old boy with recurrent nosebleeds (epistaxis) over an extended period. In addition, he showed signs of slowed weight gain and developed symptoms such as snoring and sweating during sleep. Rhinoscopy revealed a mass in the nasopharynx, and further tests confirmed the presence of an Epstein-Barr Virus-positive nasopharyngeal carcinoma.
View Article and Find Full Text PDFNeurochemical characterization of 5-HTR partial agonists with simultaneous PET-MRI.
J Cereb Blood Flow Metab
November 2024
Article Synopsis
- This study investigates the effects of different serotonin 2A receptor (5-HTR) agonists, such as psilocybin, lisuride, and 25CN-NBOH, to understand their potential in psychedelic drug applications.
- Using advanced imaging techniques like PET and phMRI on nonhuman primates, the researchers evaluated how these agonists affect brain blood flow and receptor occupancy.
- Findings suggest that mixed agonists like psilocybin and lisuride create complex blood volume responses while 25CN-NBOH leads to simpler responses, shedding light on how these drugs could be used to treat psychiatric disorders.
High-throughput screening for respiratory pathogens within pigs in Denmark; analysis of circulating porcine respiratory coronaviruses and their association with other pathogens.
Virus Res
December 2024
Article Synopsis
- Porcine respiratory coronavirus (PRCV) primarily causes mild respiratory issues in pigs, but it can lead to more serious conditions under certain circumstances.
- A study in Denmark found that around 75% of recent pig blood samples contained antibodies against PRCV, indicating a high prevalence.
- Genetic analysis showed that the current PRCV strains in Denmark are related to earlier European strains and suggest the need for further research on their impact on pig health.