, an allele of , causes tissue overgrowth in the eye.

Mutant , generated via EMS mutagenesis in , was studied by undergraduate students participating in the Fly-CURE. After inducing genetically mosaic tissue in the adult eye, mutant tissue displays a robust increase in cell division and a rough appearance. Complementation mapping and sequence analysis identified a nonsense mutation in the gene , which we named ( ) due to observed increases in red-pigmented mutant tissue compared to controls.

Determinants of selection in yeast evolved by genome shuffling.

Background: Genome shuffling (GS) is a widely adopted methodology for the evolutionary engineering of desirable traits in industrially relevant microorganisms. We have previously used genome shuffling to generate a strain of that is tolerant to the growth inhibitors found in a lignocellulosic hydrolysate. In this study, we expand on previous work by performing a population-wide genomic survey of our genome shuffling experiment and dissecting the molecular determinants of the evolved phenotype.

Teaching the Genome Generation: Bringing Modern Human Genetics into the Classroom Through Teacher Professional Development.

Teaching the Genome Generation (TtGG) is a teacher professional development program and set of high school biology lessons that support interwoven classroom instruction of molecular genetics, bioinformatics, and bioethics. Participating teachers from across New England implement the modular elements of program at a high rate in a variety of biology classrooms. Evaluation data collected over three academic years (2014/15 to 2016/17) indicate that TtGG has increased teachers' abilities to integrate complex concepts of genomics and bioethics into their high school classes.

Asymmetrical positive assortative mating induced by developmental lead (Pb) exposure in a model system, .

Anthropogenic pollutants have the potential to disrupt reproductive strategies. Little is known about how lead (Pb) exposure disrupts individual-level responses in reproductive behaviors, which are important for fitness. was used as a model system to determine the effects of: 1) developmental lead exposure on pre-mating reproductive behaviors (i.