Publications by authors named "K E Hayden"
Background: Children with medical complexity (CMC) require complex care that parents must independently provide and manage when discharged home from hospital. It is important that parents are adequately prepared to safely transition home from hospital with their child.
Method: A synthesis of findings from research articles was conducted to map and summarize available evidence on CMC and their parents' experiences of discharge from hospital to home.
Atherosclerotic cardiovascular disease remains a major cause of premature death in the UK. Lipid testing is a key tool used to assess cardiovascular risk and guide clinical management decisions. There are currently no national guidelines to provide evidence-based recommendations on lipid testing and reporting for UK laboratories and clinicians.
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- Dry deposition plays a significant role in removing reactive organic carbon from the atmosphere, impacting airborne chemical reactions and transferring this carbon to other environmental systems.
- Using aircraft measurements, researchers found that oil operations can lead to high deposition rates of organic carbon, reaching up to 100 tons per hour, with rapid lifetimes of about 4 hours that can compete with oxidation processes.
- Traditional models for gas-phase deposition may not capture all deposited organic carbon, indicating a need to consider these deposition processes in assessing the effects on freshwater ecosystems, as they contribute significantly to the overall carbon balance compared to terrestrial sources.
Importance: Metals are established neurotoxicants, but evidence of their association with cognitive performance at low chronic exposure levels is limited.
Objective: To investigate the association of urinary metal levels, individually and as a mixture, with cognitive tests and dementia diagnosis, including effect modification by apolipoprotein ε4 allele (APOE4).
Design, Setting, And Participants: The multicenter prospective cohort Multi-Ethnic Study of Atherosclerosis (MESA) was started from July 2000 to August 2002, with follow-up through 2018.
Introduction: Growing interest centers on the association between circulating ketone bodies (KB) and cognitive function, notably in aging and neurodegenerative diseases.
Methods: Associations of plasma KB with incident dementia and cognitive performances were examined among Multi-Ethnic Study of Atherosclerosis (MESA) participants. KB were measured using plasma samples collected following an overnight fasting at Exam 1 (2000-02) and detailed cognitive testing at Exam 5 (2010-2012, = 4392), Exam 6 (2016-2018, = 1838), and in MESA-MIND (2019-2021, = 2060).