Publications by authors named "K E Grund"

Article Synopsis
  • PEG is important in treating advanced Parkinson's disease through intrajejunal levodopa delivery, but its standard administration (JET-PEG) can lead to complications due to absorption area limitations and improper placement techniques.
  • High complication rates, like local infections and catheter dislocations, highlight the need for improved PEG placement and follow-up care.
  • A modified application technique and the new Hybrid-PEG method have shown effectiveness in reducing complications, emphasizing the importance of anatomical and surgical details in their implementation.*
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In this work, for the first time, the specific impedances of various injection solutions as well as the surface and tissue impedance after injection of these solutions were analyzed and compared regarding the radio-frequency surgical cutting process. The impedances of 0.9% NaCl, 4% gelatine, 6% hydroxyethyl starch, 10% glycerol/5% fructose, 10% glucose, 5% and 20% albumin, blood, and blood plasma as well as aqua destillata have been tested in vitro.

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Endoscopy training models (ETM) using artificial organs are practical, hygienic and comfortable for trainees. However, few models exist for training endoscopic retrograde cholangiopancreatography (ERCP) in patients with surgically altered anatomy. This training is necessary as the number of bariatric surgeries performed worldwide increases.

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Analysis of selected cancer genes has become an important tool in precision oncology but cannot fully capture the molecular features and, most importantly, vulnerabilities of individual tumors. Observational and interventional studies have shown that decision-making based on comprehensive molecular characterization adds significant clinical value. However, the complexity and heterogeneity of the resulting data are major challenges for disciplines involved in interpretation and recommendations for individualized care, and limited information exists on how to approach multilayered tumor profiles in clinical routine.

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