A Prospective Observational Cohort Study Comparing High-Complexity Against Conventional Pelvic Exenteration Surgery.

Conventional pelvic exenteration (PE) comprises the removal of all or most central pelvic organs and is established in clinical practise. Previously, tumours involving bone or lateral sidewall structures were deemed inoperable due to associated morbidity, mortality, and poor oncological outcomes. Recently however high-complexity PE is increasingly described and is defined as encompassing conventional PE with the additional resection of bone or pelvic sidewall structures.

Superstable lipid vacuoles endow cartilage with its shape and biomechanics.

Conventionally, the size, shape, and biomechanics of cartilages are determined by their voluminous extracellular matrix. By contrast, we found that multiple murine cartilages consist of lipid-filled cells called lipochondrocytes. Despite resembling adipocytes, lipochondrocytes were molecularly distinct and produced lipids exclusively through de novo lipogenesis.

Osteoid Osteoma in an Elderly Patient: Diagnostic Challenges.

Osteoid osteoma is a benign bone tumor commonly affecting young individuals, with a rare occurrence in older adults. It typically presents with night pain relieved by nonsteroidal anti-inflammatory drugs and is characterized radiographically by a small, radiolucent nidus surrounded by reactive sclerosis. We present a 70-year-old female patient with persistent right hip pain, initially diagnosed as arthritis, who underwent total hip arthroplasty.

Utilization of Participatory Research Theory and a National Framework to Advance a State Food Security Research Agenda: A Mixed-Methods Study.

The 2022 White House National Strategy on Hunger, Nutrition, and Health outlined goals for ending hunger in the US. Actions fell into five areas, called pillars; the goal of Pillar 5 was to enhance nutrition and food security research. This study leveraged participatory research theory and the National Strategy for developing a statewide, evidence-informed food security research agenda.

The Assessment and Prevention of Medical Device-Related Pressure Injuries in the Home Health Setting.

Medical device-related pressure injuries (MDRPIs) pose a significant risk in the home health environment, where patients may lack continuous professional oversight. Devices commonly used in the home environment with the potential to cause a MDRPI include but are not limited to nasogastric tubes, feeding tubes, nasal cannulas, nasal cannula prongs, airway pressure masks, indwelling urinary catheters, sequential compression devices, dressings, bandages, and tracheostomies. When a medical device is used for an extended period, it can lead to unrelieved pressure or edema, cause friction and/or shearing that impairs sensation, reduces circulation, and alters the microclimate.