Publications by authors named "K E Bonzel"
Effect of the dialysis fluid buffer on peritoneal membrane function in children.
Clin J Am Soc Nephrol
January 2013
Background And Objectives: Double-chamber peritoneal dialysis fluids exert less toxicity by their neutral pH and reduced glucose degradation product content. The role of the buffer compound (lactate and bicarbonate) has not been defined in humans.
Design, Setting, Participants, & Measurements: A multicenter randomized controlled trial in 37 children on automated peritoneal dialysis was performed.
Background: Regional citrate anticoagulation (RCA) is strongly recommended for adults with an increased risk of bleeding complications. The objective of this retrospective analysis was to evaluate an RCA protocol concerning feasibility and safety in intermittent high-flux haemodialysis (iHD) treatment in children and adolescents.
Methods: Eighteen children and adolescents aged 5-17 years (median 15 years) underwent 74 iHD treatment sessions with RCA.
Background And Objectives: The International Pediatric Peritonitis Registry (IPPR) was established to collect prospective data regarding peritoneal dialysis (PD)-associated peritonitis in children. In this report, we present the IPPR results that pertain to relapsing peritonitis (RP).
Design, Setting, Participants, & Measurements: This was an online, prospective entry into the IPPR of data that pertain to peritonitis cases by participating centers.
Background: Newborns with inborn errors of metabolism often present with hyperammonaemic coma, requiring prompt diagnosis and specific medical therapy, nutritional support and efficient toxin removal. Little information regarding the efficacy and safety of continuous venovenous haemodialysis (CVVHD) as an option for extracorporal ammonia detoxification in children is available.
Methods: Twenty-one patients with hyperammonaemia [19 neonates (mean age 4.