Hypertensive heart disease: quantitative evaluation of response to therapy with cine MR imaging.

Rationale And Objectives: To assess the ability of cine magnetic resonance (MR) imaging to help detect and quantity changes in left ventricular parameters in patients receiving antihypertensive therapy.

Materials And Methods: After undergoing baseline cine MR imaging of the heart, 16 (12 men, four women) hypertensive patients participating in a prospective drug trial began isradipine therapy. Follow-up serial cine MR imaging was performed at 3 months and 6 months.

[Diagnosis and follow-up of muscle injuries by means of plain and contrast-enhanced MRT: experimental and clinical studies].

Purpose: To clarify the value of plain and contrast-enhanced MRI for the diagnosis and follow-up of muscle injuries, by means of experimental and clinical studies.

Method: 24 Wistar rats were studied following standardized division of the calf muscles by means of MRI carried out on the first day, and also after one, two, three and four weeks. In addition, 16 patients with muscle injuries were examined (32 examinations), first between the first and fifth day of trauma, and subsequently over a period of two to seven weeks (average: four weeks).